A new method of getting rid of car/sea illness delivers drug through the buccal cavity in the mouth.
More and more travelers are looking for motion sickness remedies that are fast-acting and/or non-chemical. Scientists have found a new method for treating the problem more quickly, using dimenhydrinate (a known anti-nausea medication) in chewing gum.
The gum was introduced at the 2012 American Association of Pharmaceutical Scientists Annual Meeting and Exposition in Chicago this week. By being absorbed by saliva and the buccal cavity in our mouths (the space between the inside of the cheek and the gums), the drug is more quickly processed in the body, alleviating the symptoms faster.
Although dimenhydrinate is normally associated with a bitter taste, the gum is not, itself, acrid. The researcher, Mohsen Sadatrezaei, addressed this in his presentation:
The main challenge in delivering drugs through chewing gum is masking the bitter taste of its active ingredient. We have formulated dimenhydrinate as chewing gum with acceptable taste and sensory attributes. Dimenhydrinate is among the best drug candidates for treatment of motion sickness, providing a comfortable and acceptable drug delivery.
Mohsen Sadatrezaei works at the Iranian pharmaceutical company, RoshaDarou, with a team from Tehran’s Islamic Azad University School of Pharmaceutical Sciences.
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