Researchers at the Yale School of Medicine have had success with an experiment to grow new arteries

Researchers at the Yale School of Medicine have had success with an experiment to grow new arteries. They are hoping to discover a less invasive way to deal with arterial blockage, which can lead to serious surgery.

Simons and his team studied mice and zebrafish to see if they could simulate arterial formation by switching on and off two signaling pathways: ERK1/2 and PI3K.

“We found that there is cross-talk between the two signaling pathways. One half of the signaling pathway inhibits the other. When we disable the inhibitor mechanism, we are able to grow arteries,” Simons says.

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